Publications

Zavitsanou AM, Hao Y, Wu WL, Eric Bartnicki E, Pillai R, Karakousi T, Herrera A, Karatza A, Rashidfarrokhi A, Solis S, Ciampricotti M, Yeaton AH, Ivanova E, Wohlhieter CA, Buus TB, Poirier JT, Rudin CM, Wong KK, Moreira AL, Khanna KM, Tsirigos A, Papagiannakopoulos T*, Koralov SB*. KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance. Under review (pre-print: bioRxiv doi: 10.1101/2021.09.24.461709).

Ivanova EN, Devlin JC, Buus TB, Koide A, Shwetar J, Cornelius A, Samanovic MI, Herrera A, Mimitou EP, Zhang C, Desvignes L, Odum N, Smibert P, Ulrich JR, Mulligan MJ, Koide S, Ruggles KV, Herati RS*, Koralov SB*. SARS-CoV-2 mRNA vaccine elicits a potent immune response in the absence of IFN-mediated inflammation observed in COVID-19. Under review (pre-print: medRxiv doi: 10.1101/2021.04.20.21255677v2).

Gill RPK, Gantchev J, Villarreal AM, Ramchatesingh B, Netchiporouk E, Akilov OE, Odum N, Gniadecki R, Koralov SB, Litvinov IV. Understanding cell lines, patient-derived xenograft and genetically engineered mouse models used to study Cutaneous T Cell Lymphoma. Cells 2022 Feb 9;11(4):593.

Borbet TC, Pawline MB, Zhang X, Reuter S, Maher T, Li J, Iizumi T, Gao Z, Daniele M, Taube C, Koralov SB, Müller A, Blaser MJ. Early-life antibiotic exposure enhances immune responses to house dust mite antigen by altering the gut microbiota. Mucosal Immunology 2022 Jul 16. PMID: 35842561 online ahead of print.

Samanovich MI, Cornelius AR, Gray-Gaillard SL, Allen JR, Karmacharya T, Wilson JP, Hyman SW, Tuen M, Koralov SB, Mulligan MJ, Herati RS. Robust immune responses after one dose of BNT162b2 mRNA vaccine dose in SARS-CoV-2 experienced individuals. Science Translational Medicine 2021 Dec 7:eabi8961.

Buus TB, Koralov SB. Oncogenic fusions JAK up CD8+ cytotoxic CTCL. Blood. 2021 Dec9;138(23):2311-2312.

Herrera A, Cheng A, Mimitou EP, Seffens A, George D, Bar-Natan M, Heguy A, Ruggles KV, Scher J, Hymes K, Latkowski A, Ødum N, Kadin ME, Ouyang Z, Geskin LJ, Smibert P, Buus TB, Koralov SB. Multimodal single-cell analysis of cutaneous T cell lymphoma reveals distinct malignant sub-clones and tissue dependent signatures. Blood 2021 Oct 21;138(16):1456-1464. PMID: 34232982.

Lu Q, Liu J, Zhao S, Gomez Castro MF, Laurent-Rolle M, Dong J, Ran X, Damani-Yokota P, Tang H, Karakousi T, Son J, Kaczmarek ME, Zhang Z, Yeung ST, McCune BT, Chen RE, Tang F, Ren X, Chen X, Hsu JCC, Teplova M, Huang B, Deng H, Long Z, Mudianto T, Jin S, Lin P, Du J, Zang R, Su TT, Herrera A, Zhou M, Yan R, Cui J, Zhu J, Zhou Q, Wang T, Ma J, Koralov SB, Zhang Z, Aifantis I, Segal LN, Diamond MS, Khanna KM, Stapleford KA, Cresswell P, Liu Y, Ding S, Xie Q, Wang J. SARS-CoV-2 exacerbate proinflammatory responses in myeloid cells through ACE2-independent interactions via C-type lectin receptors and TTYH2. Immunity 2021 Jun8;54(6):1304-1319

Haberman RH, Herati RS, Simon D, Samanovic-Golden M, Blank R, Tuen M, Koralov SB, Arteya R, Tascilar K, Allen JR, Castillo R, Cornelius AR, Rackoff P, Solomon G, Adhikari S, Azar N, Rosenthal P, Izmirly P, Samuels J, Golden B, Reddy S, Neurath M, Schett G, Mulligan M, Scher JU. Methotrexate hampers immunogenicity to BNT162b2 mRNA vaccine in immune-mediated inflammatory disease. Annals of the Rheumatic Disease 2021 Oct;80(10):1339-1344.

Borbet TC, Hines MJ, Koralov SB. MicroRNA regulation of B cell receptor signaling. Immunol Rev. 2021 Sep 14 Nov;304(1):111-125.

Perelman SS, James DBA, Boguslawski KM, Nelson WN, Ilmain JK, Zwack EE, Prescott RA, Mohamed A, Tam K, Chan R, Narechania A, Pawline MB, Vozhilla N, Moustafa AM, Kim SY, Dittmann M, Ekiert DC, Bhabha G, Shopsin B, Planet PJ, Koralov SB, Torres VJ. Genetic variation of staphylococcal LukAB toxin determines receptor tropism. Nature Microbiology 2021 Jun;6(6):731-745.

Yang L, Lejeune A, Chang G, Scher JU, Koralov SB. Microbial-derived antigens and metabolites in spondyloarthritis. Seminars in Immunopathology. 2021 Apr;43(2):163-172.

Buus TB, Herrera A, Ivanova E, Mimitou E, Cheng A, Papagiannakopoulos T, Smibert P, Ødum N, Koralov SB. Improving oligo-conjugated antibody signal in multimodal single-cell analysis. eLife Apr 16;10e61973. (preprint: bioRxiv doi: 10.1101/2020.06.15.153080).

Willerslev-Olsen, Gjerdrum LM, Lindahl LM, Buus TB, Pallesen EMH, Gluud M, Bzorek M, Nielsen BS, Kamstrup MR, Bonefeld CM, Krejsgaard T, Vermeer M, Geisler C, Koralov SB, Litman T, Becker JC, Woetmann A, Iversen L, Ødum N. Staphylococcus aureus induces STAT5 dependent miR-155 expression in cutaneous T cell lymphoma (CTCL). J. of Investigative Dermatology 2021 Apr 13:S0022-202X(21)01148-9.

Wu BG, Kapoor B, Cummings KJ, Stanton ML, Nett RJ, Kreiss K, Abraham JL, Colby TV, Franko AD, Green FHY, Sanyal S, Clemente JC, Gao Z, Coffre M, Heguy A, Li Y, Slulaiman I, Borbet TC, Koralov SB,Tallaksen RJ, Wendland D, Bachelder VD, Boylstein RJ, Park JH, Cox-Ganser JM, Virji A, Crawford JA, Edwards NT, Veillette M, Duchaine C, Warren K, Lundeen S, Weissman DN, Blaser MJ, Segal LN. Evidence for environmental-human microbiota transfer in workers at a manufacturing facility with a cluster of B-cell bronchiolitis-alveolar ductitis and emphysema. American Journal of Respiratory and Critical Care 2020 Dec. 15;202(12):1678-1688.

Hines MJ, Coffre M, Panduro M, Wigton EJ, Tegla C, Osario-Vasquez V, Kageyama R, Benhamou D, Perez O, Bajwa S, McManus MT, Ansel KM, Melamed D, Koralov SB. miR-29 sustains B cell survival and controls terminal differentiation via regulation of PI3K signaling. Cell Reports 2020 Dec 1;33(9):108436.

Tsay JJ, Wu BG, Sulaiman I, Gershner K, Schulger R, Li Y, Yie TA, Meyn P, Olsen E, Perez L, Franca B, Carpenito J, Iizumi T, El-Ashmawy M, Badri M, Morton JT, Shen N, He L, Michaud G, Rafeq S, Bessich J, Smith RL, Sauthoff H, Felner K, Pillai R, Zavtisanou A, Koralov SB, Mezzano V, Loomis C, Moreira AL, Moore W, Tsirigos A, Heguy A, Rom WN, Sterman DH, Pass HI, Clemente JC, Li H, Bonneau R, Wong KK, Papagiannakopoulos T, Segal L. Lower airway dysbiosis affects lung cancer progression. Cancer Discovery 2020 Nov 11:CD-20-0263.

Wu BG, Sulaiman I, Tsay JJ, Perez L, Franca B, Li Y, Wang J, Gonzalez AN, El-Ashmawy M, Carpenito J, Olsen E, Sauthoff M, Yie K, Liu X, Shen N, Clemente JC, Kapooer B, Zangari T, Mezzano V, Loomis C, Weiden MD, Koralov SB, D’Armiento J, Ahuja SK, Wu XR, Weiser JN, Segal LN. Episodic Aspiration with Oral Commensals Induces a MyD88-dependent, Pulmonary Th17 Response that Mitigates Susceptibility toStreptococcus pneumoniae. American Journal of Respiratory Critical Care Medicine 2020 Nov 9 epub ahead of print.

Tam K, Lacey KA, Devlin JC, Coffre M, Sommerfield A, Chan R, O’Malley A, Koralov SB, Loke P, Torres VJ. Targeting leukocidin-mediated immune evasion protects mice from Staphyloccocus aureusbacteremia. J. of Exp. Med. 2020 Sep 7;217(9):e20190541.

Chen ML, Sun A, Cao W, Eliason A, Mendez KM, Getzler AJ, Tsuda S, Diao H, Bruno NE, Kim SY, Pipkin ME, Koralov SB*, Sundrud MS*. (* co-corresponding authors) Physiologic expression and function of the multidrug transporter MDR1 in cytotoxic T lymphocytes. J. of Exp. Med. 2020 May4;217(5):e20191388.

Blumel E, Munir Ahman S, Nastasi C, Willerslev-Olsen A, Gluud M, Fedholm S, Hu T, Surewaard BGL, Lindahl LM, Fogh H, Koralov SB, Rahbek Gjerdrum LM, Clark RA, Iversen L, Krejsgaard T, Bonefeld CM, Geisler C, Becker JC, Woetmann A, Andersen MH, Buus TB, Ødum N. Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma. Oncoimmunology 2020 Apr 17;9(1):1751561.

Boguslawski KM, McKeown AN, Day CJ, Tam K, Vozhilla N, Kim SY, Jennings MP, Koralov SB, Elde NC, Torres VJ. Exploiting species specificity to understand the tropism of a human specific toxin. Science Advances 2020 Mar 11;6(11):eaax7515.

Shin B, Benavides GA, Geng J, Koralov SB, Hu H, Darley-Usmar VM, Harrington LE. Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between pathogenic Th17 and regulartory T cells. Cell Reports 2020 Feb 11;30(6):1898-1909.

Seffens A, Herrera A, Tegla C, Buus TB, Hymes KB, Ødum N, Geskin LJ, Koralov SB. STAT3 Dysregulation in Mature T and NK Cell Lymphomas. Cancers, 2019 Nov 2; 11(11) E1711.

LeBoeuf SE, Wu WL, Karakousi TR, Karadal B, Jackson SR, Davidson SM, Wong K, Koralov SB, Sayin VI, Papagiannakopoulos T. Activation of oxidative stress response in cancer generates a druggable dependency on exogenous non-essential amino acids. Cell Metabolism, 2019 Feb 4;31(2):339-350.

Heichler C, Scheibe K, Schmied A, Geppert CI, Schmid B, Wirtz S, Thoma OM, Kramer V, Waldner MJ, Büttner C, Farin HF, Knieling F, Merkel S, Grüneboom A, Gunzer M, Grützmann R, Rose-John S, Koralov SB, Kollias G, Vieth M, Hartmann A, Greten FR, Neurath MF, Neufert C. STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumor development and correlates with prognosis. Gut, 2019 Nov 4 Epub ahead of print.

Herrera A, Fredholm S, Cheng A, Mimitou EP, Seffens A, Bar-Natan M, Sun A, Latkowski J, Willerslew-Olsen A,  Buus T, Gluud M, Krejsgaard T, Torres-Rusillo S, Bonefeld CM, Woetmann A, Geisler C, Geskin LJ, Ouyang Z, Smibert P, Ødum N*, Koralov SB*. (* co-corresponding authors) Low SATB1 expression promotes IL-5 and IL-9 expression in Sezary Syndrome. Journal of Investigative Dermatology, 2019 Aug 26 Epub ahead of print.

Mimitou E, Cheng A, Montalbano A, Hao S, Stoeckius M, Herrera A, Papalexi E, Ouyang Z, Satija R, Sanjana N, Koralov SB, Smibert P. Expanding the CITE-seq tool-kit: Detection of proteins, transcriptomes, clonotypes and perturbations with multiplexing, in a single assay. Nature Methods 2019, May; 16(5): 409-412. 

Yen WF, Vaidyanathan B, Chaudhry A, Yewdell W, Sun A, Coffre M, Pucella J, Rudensky A, Koralov SB, Chaudhuri J. Distinct requirement of CHD4 during B cell development and antibody response. Cell Reports 2019 Apr 20;27(5): 1472-1486.e5.

Kaufman U, Kahlfuss S, Ivanova E, Koralov SB, Feske S. Calcium signaling controls pathogenic Th17 cell-mediated inflammation by regulating mitochondrial metabolism. Cell Metabolism 2019, Cell Metabolism 2019, May 7;29(5): 1104-1118.

Lubkin A, Lee WL, Alonzo 3rd F, Wang C, Aligo J, Keller M, Girgis NM, Reyes-Robles T, Chan R, O’Malley A, Buckley P, Vozhilla N, Vasquez M, Su J, Sugiyama M, Stephen Yeung, Coffre M, Bajwa S, Chen E, Martin P, Kim SY, Loomis C, Worthen GS, Shopsin B, Khanna K, Weinstock D, Lynch AS, Koralov SB, Loke P, Cadwell K, and Torres VJ. Staphylococcus aureus leukocidins target endothelial Duffy to cause lethality. Cell Host 2019, March 13;25(3): 463-470.e9. 

Cantor DJ, King B, Blumenberg L, DiMauro T, Aifantis I, Koralov SB, Skok JA, David G. Impaired expression of rearranged immunoglobulin genes and compromised p53 activation lead to a block in B cell development in Bmi1 null mice. Cell Reports 2019 Jan 2; 26(1):109-118. 

Evans-Martin H, Rogier R, Koralov SB, Roeleveld D, van der Karaan PM, Scher JU, Koenders MI, Abdollahi-Roodsaz S. Involvement of T helper 17 cells in inflammatory arthritis depends on the host intestinal microbiota. Arthritis and Rheumatology. 2018 Dec; 70(12): 1971-1983.

Wong SY, Coffre M, Ramanan D, Hines M, Gomez LE, Peters L, Schadt E, Koralov SB* and Cadwell K* (* co-corresponding authors). B cell defects observed in Nod2 knockout mice are a consequence of a Dock2 mutation frequently found in inbred strains. J. of Immunol. 2018 Sep 1;201(5):1442-1451.

Yang L, Fanok MH, Mediero-Munoz A, Fogli LK, Abdollahi S, Cronstein BN, Scher JU, Koralov SB. Augmented Th17 differentiation leads to cutaneous and musculoskeletal inflammation in a novel model of psoriatic arthritis. Arthritis and Rheum. Arthritis and Rheum. 2018 Jun;70(6):885-867.

Fredholm S, Willerslev-Olsen A, Met O, Kubat L, Gluud M, Mathiasen SL, Friese C, Blümel E, Petersen DL, Hu T, Nastasi C, Lindahl LM, Buus TB, Krejsgaard T, Wasik MA, Kopp KL, Koralov SB, Bonefeld CM, Geisler C, Woetmann A, Iversen L, Becker JC, Ødum N. Special AT rich-binding1 protein (SATB1) in malignant T cells. Journal of Invest Dermatol. 2018 May Epub ahead of print.

Fanok MH, Sun A, Fogli LK, Narendran V, Eckstein M, Kannan K, Dolgalev I, Lazaris C, Heguy A, Laird ME, Sundrud M, Liu C, Lacruz RS, Kutok J, Aifantis I, Latkowski J, Ødum N, Hymes KB. Goel S. and Koralov SB. Role of dysregulated cytokine signaling and bacterial triggers in the pathogenesis of Cutaneous T Cell Lymphoma. Journal of Investig. Dermatol. 2018 May; 138(5):1116-1125.

Cao W, Kayama H, Chen ML, Delmas A, Sun A, Kim SY, Rangarajan ES, McKevitt K, Beck AP, Jackson CB, Oikonomopoulos A, Lacey PN, Martinez GJ, Izard T, Lorenz RG, Rodriguez-Palacios A, Cominelli F, Abreu MT, Hommes DW, Koralov SB, Takeda K, Sundrud MS. The xenobiotic transporter Mdr1 permits T cell adaptation to bile acid reabsorption in the ileum. Immunity 2017 Dec 19;47(6):1182-1196.

Coffre M, Koralov SB. miRNAs in B Cell Development and Lymphomagenesis. Trends Mol Med. 2017 Aug;23(8):721-736.

Coffre M, Benhamou D, Rieß D, Blumenberg L, Snetkova V, Hines MJ, Chakraborty T, Bajwa S, Jensen K, Chong MMW, Getu L, Silverman GJ, Blelloch R, Littman DR, Calado D, Melamed D, Skok JA, Rajewsky K, Koralov SB. miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation. Cell Rep. 2016 Nov 22;17(9):2271-2285.

Lindhal LM, Fedholm S, Joseph C, Nielsen BS, Jonson L, Willerslev-Olsen A, Gluud M, Blümel E, Petersen DL, Sibbesen N, Hu T, Krejsgaard T, Jæhger D, Persson JL, Mongan N, Wasik MA, Litvinov IV, Sasseville D, Koralov SB, Bonefeld CM, Geisler C, Woetmann A, Ralfkiaer E, Iversen L, Ødum N. STAT5 induces miR-21 expression in cutaneous T cell lymphoma. Oncotarget. 2016, Jun 18.

Orlanski S, Labi V, Reizel Y, Spiro A, Lichtenstein M, Levin-Klein R, Koralov SB, Skversky Y, Rajewsky K, Cedar H, Bergman Y. Tissue-specific DNA demethylation is required for proper B-cell differentiation and function. PNAS 2016, May 3;113(18):5018-23.

Segal LN, Clemente JC, Tsay JJ, Koralov SB, Keller BC, Wu BG, Li Y, Shen N, Ghedin E, Morris A, Diaz P, Huang L, Wikoff WR, Ubeda C, Artacho A, Rom WN, Sterman DH, Collman RG, Blaser MJ, Weiden MD. Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype. Nature Microbio. 2016, Apr 4;1:16031.

Fredholm S, Litvinov IV, Mongan NP, Schiele S, Willerslev-Olsen A, Petersen DL, Krejsgaard T, Sibbesen N, Nastasi C, Bonefeld CM, Persson JL, Straten PT, Andersen MH, Koralov SB, Wasik MM, Geisler C, Sasseville D, Woetmann A, Ødum N. The Expression of IL-21 Is Promoted by MEKK4 in Malignant T Cells and Associated with Increased Progression Risk in Cutaneous T-Cell Lymphoma. J Invest Dermatol. 2016 Jan 21. Epub ahead of print.

Willerslev-Olsen A, Krejsgaard T, Lindahl LM, Litvinov IV, Fredholm S, Petersen DL, Nastasi C, Gniadecki R, Mongan NP, Sasseville D, Wasik MA, Bonefeld CM, Geisler C, Woetmann A, Iversen L, Kilian M, Koralov SB, Odum N. Staphylococcal enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma. Blood. 2016 Mar 10;127(10):1287-96. doi: 10.1182/blood-2015-08-662353. Epub 2016 Jan 5.

Pylayeva-Gupta Y, Das S, Handler JS, Hajdu CH, Coffre M, Koralov SB, Bar-Sagi D. IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia. Cancer Discov. 2016 Mar;6(3):247-55. doi: 10.1158/2159-8290.CD-15-0843. Epub 2015 Dec 29.

Wright KL, Adams JR, Liu JC, Loch AJ, Wong RG, Jo CEB, Beck LA, Santhanam DR, Weiss L, Mei X, Lane TF, Koralov SB, Done SJ, Woodgett JR, Zacksenhaus E, Pingzhao H and Egan SE. Ras signaling is a key determinant for metastatic dissemination and poor survival of luminal breast cancer patients. Cancer Res. 2015 Sep 23 Epub ahead of print.

Kang J, Lienhard M, Pastor WA, Chawla A, Novotny M, Tsagaratou A, Lasken RS, Thompson EC, Surani MA, Koralov SB, Kalantry S, Chavez L and Rao A. Simultaneous deletion of Tet1 and Tet3 increases transcriptome variability in early embryogenesis. PNAS 2015 Aug 4; 112(31):E4236-45.

Zhang B, Calado DP, Wang Z, Fröhler S, Köchert K, Qian Y, Koralov SB, Schmidt-Supprian M, Sasaki Y, Unitt C, Rodig S, Chen W, Dalla-Favera R, Alt FW, Pasqualucci L, Rajewsky K. An oncogenic role for alternative NF-?B signaling in DLBCL revealed upon deregulated Bcl6 expression. Cell Rep. 2015, May 5; 11(5):715-26

Danielson LS, Reavie L, Coussens M, Davalos-Vega V, Castillo-Martino M, Guijarrow M, Coffre M, Cordon-Cardo C, Aifantis I, Ibrahim S, Liu C, Koralov SB* and Hernando E*. Limited miR-17~92 overexpression drives hematologic malignancies. Leuk Research. 2014, Dec 10 [Epub ahead of print] doi: 10.1016/j.leukres.2014.12.002 (* co-corresponding authors)

Sun A, Novobrantseva TI, Coffre M, Hewitt SL, Jensen K, Skok JA, Rajewsky K and Koralov SB. VH replacement in primary immunoglobulin repertoire diversification. PNAS 2015, Feb 3; 112(5):E458-66.

Backer I, Koralov SB, Wirtz S, Kitowski V, Billmeier U, Martini E, Hofmann K, Wittkopf N, Brecht K, Waldner M, Neurath MF, Becker C and Neufert C. STAT3 activation in Th17 and Th22 cells controls IL-22 mediated epithelial host defense during infectious colitis. J Immunol. 2014 Oct 1; 193(7):3779-91.

Krejsgaard T, Willerslev-Olsen A, Lindahl LM, Bonefeld CM, Koralov SB, Geisler C, Wasik MA, Gniadecki R, Kilian M, Iversen L, Woetmann A, Odum N. Staphylococcal enterotoxins promote lymphoma-associated immune dysregulation by modulating benign and malignant T-cell interactions. Blood 2014 Jul 31; 124(5):761-70.

Kaplinsky J, Li A, Sun A, Coffre M, Koralov SB* and Araout R*. Antibody repertoire deep-sequencing reveals antigen-independent selection in maturing B cells. PNAS 2014, Jun24;111(25): 2622-9. *equal contribution

Carlson TJ, Pellerin A, Koralov SB, Rao A and Sundrud MS. Halofuginone-induced amino acid starvation regulates IL-23-dependent Th17 effector function and ameliorates established autoimmune inflammation. J Immunol. 2014 Mar 1; 192(5):2167-76.

Fogli LK, Sundrud MS, Goel S, Bajwa S, Jensen K, Derruder E, Sun A, Coffre M, Uyttenhove C, Van Snick J, Schmidt-Supprian M, Rao A, Grunig G, Durbin J, Casola SS, Rajewsky K and Koralov SB. T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia. J Immunol. 2013 Sep 15; 191(6):3100-11

Krejsgaard T, Litvinov IV, Wang Y, Xia L, Willerslev-Olsen A, Koralov SB, Kopp KL, Bonefeld CM, Wasik MA, Geisler C, Woetmann A, Zhou Y, Sasseville D and Odum N. Elucidating the role of interleukin-17F in cutaneous T-cell lymphoma. Blood 2013 Aug 8;122(6):943-50.

Ko M, Bandukwala HS, Ana J, Lamperti ED, Thompson EC, Hastie R, Tsangaratou A, Rajewsky K, Koralov SB, and Rao A. Ten-eleven-translocation 2 (Tet2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. PNAS 2011 Aug 30; 108(35): 14566-71.

Arnaout R, Lee W, Cahill P, Honan T, Sparrow T, Weiand M, Nusbaum C, Rajewsky K and Koralov SB High-resolution description of antibody heavy-chain repertoires in humans. PLOS One 2011 Aug 6(8):e22365

Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A. Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response. Science. 2009 Jun 5;324(5932):1334-8. PMCID: PMC2803727.

Koralov SB, Muljo SA, Galler GR, Krek A, Chakraborty T, Kanellopoulou C, Jensen K, Cobb BS, Merkenschlager M, Rajewsky N, Rajewsky K. Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell. 2008 Mar 7;132(5):860-74.

Mesaros A*, Koralov SB*, Rother E, Wunderlich FT, Ernst MB, Barsh GS, Rajewsky K, Brüning JC. Activation of Stat3 signaling in AgRP neurons promotes locomotor activity. Cell Metab. 2008 Mar;7(3):236-48. *equal contribution

Koralov SB, Novobrantseva TI, Königsmann J, Ehlich A, Rajewsky K. Antibody repertoires generated by VH replacement and direct VH to JH joining. Immunity. 2006 Jul;25(1):43-53.

Koralov SB, Novobrantseva TI, Hochedlinger K, Jaenisch R, Rajewsky K. Direct in vivo VH to JH rearrangement violating the 12/23 rule. J Exp Med. 2005. 7;201(3):341-8. PMCID: PMC1237122.